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Ibogaine – Legal status

By on Friday, June 10th, 2011 | No Comments

Ibogaine and its salts were regulated by the U.S. Food and Drug Administration in 1967 pursuant to its enhanced authority to regulate stimulants, depressants, and hallucinogens granted by the 1965 Drug Abuse Control Amendments (DACA) to the Federal Food, Drug, and Cosmetic Act. In 1970, with the passage of the Controlled Substances Act, it was [...]

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Ibogaine – Psychoactive effects

By on Thursday, June 9th, 2011 | No Comments

At doses of around 3–5 mg/kg of body weight, ibogaine has a mild stimulant effect. The high-dose ibogaine experience of 10 mg/kg or greater most commonly occurs as two distinct phases: the visual phase and the introspective phase The visual phase is characterized by open-eye visuals, closed-eye visuals, and dreamlike sequences. Objects may be seen as distorted, [...]

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Drug

By on Monday, March 7th, 2011 | Comments Off

Drug Coffee is the most widely used psychoactive drug beverage in the world. In 1999 the average consumption of coffee was 3.5 cups per day per U.S. citizen. Wine is a common alcoholic beverage. A drug, broadly speaking, is any substance that, when absorbed into the body of a living organism, alters normal bodily function.There [...]

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Ibogaine – Pharmacodynamics

By on Monday, February 7th, 2011 | Comments Off

Among recent proposals for ibogaine mechanisms of action is activation of the glial cell line-derived neurotrophic factor (GDNF) pathway in the ventral tegmental area (VTA) of the brain. The work has principally been accomplished in preclinical ethanol research, where 40 mg/kg of ibogaine caused increases of RNA expression of GDNF in keeping with reduction of ethanol [...]

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Ibogaine – Formulations

By on Tuesday, January 18th, 2011 | Comments Off

In Bwiti religious ceremonies, the rootbark is pulverized and swallowed in large amounts to produce intense psychoactive effects. In Africa, iboga rootbark is sometimes chewed, which releases small amounts of ibogaine to produce a stimulant effect. Ibogaine is also available in a total alkaloid extract of the Tabernanthe iboga plant, which also contains all the [...]

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