Tag archives for Drug addiction

Ibogaine – Therapeutic uses

Treatment for opiate addiction The most-studied therapeutic effect of ibogaine is the reduction or elimination of addiction to opioids. An integral effect is the alleviation of symptoms of opioid withdrawal. Research also suggests that ibogaine may be useful in treating dependence on other substances such as alcohol, methamphetamine, and nicotine and may affect compulsive behavioral patterns not involving substance abuse or chemical dependence. Proponents of ibogaine treatment for drug addiction have established formal and informal clinics or self-help groups in Canada, Mexico, the Caribbean, Costa Rica, the Czech Republic, France, Slovenia, the Netherlands, Brazil, South Africa, the United Kingdom and New Zealand, where ibogaine is administered as an experimental compound. There also exist clandestine drug-treatment facilities in the countries where it is illegal. Many users of ibogaine report experiencing visual phenomena during a waking dream state, such as instructive replays of life events that led to their addiction, while others report therapeutic shamanic visions that help them conquer the fears and negative emotions that might drive their addiction. It is proposed that intensive counseling, therapy and aftercare during the interruption period following treatment is of significant value. Some individuals require a second or third treatment session with ibogaine over the course of the next 12 to 18 months. A minority of individuals relapse completely into opiate addiction within days or weeks. A comprehensive article (Lotsof 1995) on the subject of ibogaine therapy detailing the procedure, effects and aftereffects is found in "Ibogaine in the Treatment of Chemical Dependence Disorders: Clinical…
Continue Reading

Ibogaine – Pharmacology

The pharmacology of ibogaine is quite complex, affecting many different neurotransmitter systems of its fairly low potency at any of its target sites, ibogaine is used in doses anywhere from 5 mg/kg of body weight for a minor effect to 30 mg/kg in the cases of strong polysubstance addiction. It is unknown whether doses greater than 30 mg/kg in humans produce effects that are therapeutically beneficial, medically risky, or simply prolonged in duration. In animal neurotoxicity studies, there was no observable neurotoxicity of ibogaine at 25 mg/kg, but at 50 mg/kg, one-third of the rats had developed patches of neurodegeneration, and at doses of 75 mg/kg or above, all rats showed a characteristic pattern of degeneration of Purkinje neurons, mainly in the cerebellum. While caution should be exercised when extrapolating animal studies to humans, these results suggest that neurotoxicity of ibogaine is likely to be minimal when ibogaine is used in the 10–20 mg/kg range typical of drug addiction interruption treatment regimes, and indeed death from the other pharmacological actions of the alkaloids is likely to occur by the time the dose is high enough to produce consistent neurotoxic changes. Pharmacodynamics Ibogaine affects many different neurotransmitter systems simultaneously. Noribogaine is most potent as a serotonin reuptake inhibitor. It acts as a moderate κ-opioid receptor agonist and weak µ-opioid receptor agonist or weak partial ;It is possible that the action of ibogaine at the kappa opioid receptor may indeed contribute significantly to the psychoactive effects attributed to ibogaine ingestion; Salvia divinorum, another plant recognized for its strong hallucinogenic properties, contains the chemical salvinorin A, which is a…
Continue Reading

Public health definitions

Public health practitioners have attempted to look at drug abuse from a broader perspective than the individual, emphasizing the role of society, culture and availability. Rather than accepting the loaded terms alcohol or drug "abuse," many public health professionals have adopted phrases such as "substance and alcohol type problems" or "harmful/problematic use" of drugs. The Health Officers Council of British Columbia — in their 2005 policy discussion paper, A Public Health Approach to Drug Control in Canada — has adopted a public health model of psychoactive substance use that challenges the simplistic black-and-white construction of the binary (or complementary) antonyms "use" vs. "abuse". This model explicitly recognizes a spectrum of use, ranging from beneficial use to chronic dependence (see diagram ). Source: A Public Health Approach to Drug Control in Canada, Health Officers Council of British Columbia, 2005 Stop Alcohol and Drug Addiction
Continue Reading
Drug Addiction

Locating Drug Addiction Help

Locating Drug Addiction Help The shock of getting made aware that there is a drug addict in your household will lead to the addict at destroying the household bond, beginning with you. You will be in no position to assist that household member until you can assist oneself to get previous the initial shock of their addiction. Use of Drugs: There are a quantity of medicines that are formulated to assist sufferers fight their addiction and craving for different drugs. They also assist to lessen the magnitude of the withdrawal effects that are at instances very severe. They work ideal when coupled with different physical activities. Enabling is a typical response to addiction that takes numerous types. It permits the alcoholic or drug addict to keep away from the consequences of his or her substance abuse and behavior. The enabler is a pal or household member who tries to assist the alcoholic or drug addict and who will lie for and rescue the substance abuser or alcoholic from different calamities. Even though the enabler could consider he or she is helping the person with an addiction the opposite is accurate. Enablers permit the disease of addiction to progress to a lot more acute levels. Denial can also keep men and women from recognizing their depression ??? 1 of the most typical causes of addiction and relapse. It could look strange that a depressed person would deny their own feelings, but there is a selection of causes why this occurs. In…
Continue Reading