Tabernanthine – Tabernanthe Iboga

Tabernanthine - Tabernanthe Iboga


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Skeletal formula of tabernanthine
Ball-and-stick model of the tabernanthine molecule
Clinical data
ATC code
  • none
CAS Number
PubChem CID
Chemical and physical data
Formula C20H26N2O
Molar mass 310.43 g/mol g·mol−1
3D model (JSmol)
Tabernanthine is an alkaloid found in Tabernanthe iboga.[1] It has been used in laboratory experiments to study how addiction affects the brain.[2] Tabernanthine persistently reduced the self-administration of cocaine and morphine in rats.[3]

See also[edit]


  1. ^ Bartlett, M. F.; Dickel, D. F.; Taylor, W. I. (1958). “The Alkaloids of Tabernanthe iboga. Part IV.1 The Structures of Ibogamine, Ibogaine, Tabernanthine and Voacangine – Journal of the American Chemical Society (ACS Publications)”. Journal of the American Chemical Society80: 126–136. doi:10.1021/ja01534a036.
  2. ^ Levi MS, Borne RF (October 2002). “A review of chemical agents in the pharmacotherapy of addiction”. Curr. Med. Chem9 (20): 1807–18. doi:10.2174/0929867023368980PMID 12369879.
  3. ^ Glick SD, Kuehne ME, Raucci J, Wilson TE, Larson D, Keller RW Jr, Carlson JN (September 1994). “Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum”. Brain Res657 (1–2): 14–22. doi:10.1016/0006-8993(94)90948-2PMID 7820611.

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